In Virtual machines with disk size larger than 256GB in VMFS5 and larger than 2.5TB in VMFS6, you see below symptoms

• .Host becomes unresponsive, cannot restart specific hung virtual machines.
• Host requires a reboot to restart the virtual machines.
• In the /var/log/vmkernel.log file, you see entries similar to:….. cpu46:712802)WARNING: VSCSI: 3488: handle 19192(vscsi0:1):WaitForCIF: Issuing reset; number of CIF:1
  ….. cpu38:65988)VSCSI: 2891: handle 19192(vscsi0:1):Reset [Retries: 0/0] from (vmm0:wp-02)
  ….. cpu46:712802)WARNING: VSCSI: 3488: handle 19192(vscsi0:1):WaitForCIF: Issuing reset; number of CIF:1
  ….. cpu51:712223)PVSCSI: 2642: scsi0:0: ABORT ctx=0xed
  ….. cpu36:173183)VSCSI: 2611: handle 19086(vscsi0:0):Reset request on FSS handle 9173930292 (0 outstanding commands) from (vmm0:wp-02)
  ….. cpu61:65988)VSCSI: 2679: handle 19086(vscsi0:0):Completing reset (0 outstanding commands)
  ….. cpu13:66610)ScsiDeviceIO: 2948: Cmd(0x439690e250c0) 0x85, CmdSN 0x3022 from world 68172 to dev “naa.61866xxxxxxxx” failed H:0x0 D:0x2 P:0x0 Valid sense data: 0x5 0x20 0x0.
  ….. cpu57:173183)PVSCSI: 2642: scsi0:0: ABORT ctx=0xee
  ….. cpu57:173183)VSCSI: 2611: handle 19086(vscsi0:0):Reset request on FSS handle 9173930292 (0 outstanding commands) from (vmm0:wp-02)
  ….. cpu37:1100750)WARNING: VSCSI: 3497: handle 8263(vscsi0:0):WaitForCIF: Issuing reset; number of CIF:33
  ….. cpu37:1100750)WARNING: VSCSI: 2645: handle 8263(vscsi0:0):Ignoring double reset
  ….. cpu5:65891)VSCSI: 2891: handle 8263(vscsi0:0):Reset [Retries: 1/0] from (vmm0:vmOS_7.3)
  ….. cpu5:65891)VSCSI: 2891: handle 8263(vscsi0:0):Reset [Retries: 2/0] from (vmm0:vmOS_7.3)
  ….. cpu5:65891)VSCSI: 2891: handle 8263(vscsi0:0):Reset [Retries: 3/0] from (vmm0:vmOS_7.3)
  ….. cpu5:65891)VSCSI: 2891: handle 8263(vscsi0:0):Reset [Retries: 4/0] from (vmm0:vmOS_7.3)